NutriSystem Shake Ingredients
They provide two different diet plans, one for diabetics and one for vegetarians. It is also preferred by those who are always busy and on the go. For a run down of various natural and artificial sweeteners, see this article from Nutrition Action. If protein were the only thing in the shake that curbed hunger, I'd say it was over priced. Is the effect of fructose blunted because of the fiber that is also in the shake? The author of this review of research noted grams was appropriate for helping weigh loss.
Manufacturer Information and Claims about Nutrisystem Protein Shakes
They found no difference in appetite between groups (8). Overall, I looked at 4 more studies. Two of them showed weight loss of a few pounds over a period of 8 weeks (9, 10), but the other two showed no effect (11, 12).
So… unfortunately, the weight loss effects appear to be both weak and inconsistent.